Pneumocystis jirovecii Pneumonia in an Immunocompetent Japanese Man: A Case Report and Literature Review

Author:

Ide Hiromi1ORCID,Yamaji Yoshikazu2,Tobino Kazunori1,Okahisa Masanobu1,Murakami Kojin1,Goto Yuki1,Sueyasu Takuto1,Nishizawa Saori1,Yoshimine Kohei1,Munechika Miyuki1ORCID,Oya Masafumi3,Hiraki Yuka3

Affiliation:

1. Department of Respiratory Medicine, Iizuka Hospital, Japan

2. Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Japan

3. Department of Pathology, Iizuka Hospital, Japan

Abstract

We herein report the case of a 37-year-old immunocompetent man who died from Pneumocystis jirovecii pneumonia (PCP). He was initially treated for an acute exacerbation of interstitial pneumonia; however, the elevation of the patient’s serum (1-3) β-D glucan (BG) level suggested the possibility of PCP and sulfamethoxazole trimethoprim was added. A postmortem pathological examination and retrospective Grocott's methenamine silver (GMS) staining of the bronchoalveolar lavage fluid (BALF), which was obtained on the day of admission, revealed PCP. The present case suggests that it is essential to perform a BG assay and GMS staining of BALF specimens when patients show diffuse ground-glass opacity on chest computed tomography, regardless of their immune status.

Publisher

Hindawi Limited

Subject

Pulmonary and Respiratory Medicine

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