1,3,4-Thiadiazole Derivatives. Part 91. Synthesis and Biological Activity of Metal Complexes of 5-(2-Aminoethyl)-2-Amino-1,3,4-Thiadiazole-Reference-Cited by-同舟云学术

1,3,4-Thiadiazole Derivatives. Part 91. Synthesis and Biological Activity of Metal Complexes of 5-(2-Aminoethyl)-2-Amino-1,3,4-Thiadiazole

Published:1996-01-01 Issue:5 Volume:3 Page:227-232
ISSN:0793-0291
Container-title:Metal-Based Drugs
language:en
Short-container-title:Metal-Based Drugs

Author:

Barboiu Mihai¹,Cimpoesu Marilena²,Guran Cornelia³,Supuran Claudiu T.⁴

Affiliation:

1. Research Center for Macromolecular Materials and Membranes, Spl. Independentei 206, Bucharest 79611, Romania

2. University of Bucharest, Department of Inorganic Chemistry, Str. Dumbrava Rosie 23, Bucharest, Romania

3. Polytechnic University of Bucharest, Department of Inorganic Chemistry, Polizu 1, Bucharest 79611, Romania

4. Università degli Studi, Laboratorio di Chimica Inorganica e Bioinorganica, Via Gino Capponi 7, Florence I-50121, Italy

Abstract

Metal complexes of the title ligand (L) containing Co(II), Ni(II) and Cu(II) were prepared and characterized by elemental analysis, IR, electronic spectroscopy and conductimetry. The new derivatives, possessing the following formulae, CuL2(OH)2, NiL2Cl2, and [Co2LCl4]n showed in vitro antifungal activity against Aspergillus and Candida spp.

Publisher

Hindawi Limited

Subject

Inorganic Chemistry,Drug Discovery,Pharmacology,Toxicology

Link

http://downloads.hindawi.com/archive/1996/273937.pdf

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