Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Author:

Sakaue Takaaki1,Okuno Yosuke1ORCID,Mukai Kosuke1ORCID,Fujita Shingo1,Kozawa Junji1,Nishizawa Hitoshi1,Matsuoka Taka-Aki1,Iwahashi Hiromi12,Norikazu Maeda13,Yamazaki Yuto4,Sasano Hironobu4,Otsuki Michio1ORCID,Shimomura Iichiro1

Affiliation:

1. Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

2. Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

3. Department of Metabolism and Atherosclerosis, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan

4. Department of Pathology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan

Abstract

A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

Publisher

Hindawi Limited

Subject

Endocrinology, Diabetes and Metabolism

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Adrenal cysts: an emerging condition;Nature Reviews Endocrinology;2023-04-24

2. Overview of the 2022 WHO Classification of Adrenal Cortical Tumors;Endocrine Pathology;2022-03

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