Chinese HerbAstragalus membranaceusEnhances Recovery of Hemorrhagic Stroke: Double-Blind, Placebo-Controlled, Randomized Study

Author:

Chen Chun-Chung123,Lee Han-Chung123,Chang Ju-Hsin4,Chen Shuang-Shuang1,Li Tsai-Chung5,Tsai Chang-Hai36,Cho Der-Yang13,Hsieh Ching-Liang789

Affiliation:

1. Department of Neurosurgery, China Medical University Hospital, Taichung 40402, Taiwan

2. Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan

3. School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan

4. Department of Anesthesiology, China Medical University Hospital, Taichung 40402, Taiwan

5. Graduate Institute of Biostatistics, College of Public Health, China Medical University, Taichung 40402, Taiwan

6. Division of Pediatric Neurology, Department of Pediatrics, China Medical University, Taichung 40402, Taiwan

7. Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan

8. Acupuncture Research Center, China Medical University, Taichung 40402, Taiwan

9. Department of Chinese Medicine, China Medical University Hospital, Taichung 40402, Taiwan

Abstract

We tested the effect ofAstragalus membranaceus(AM) on acute hemorrhagic stroke. Seventy-eight patients were randomly assigned to Group A (3 g of AM three times/day for 14 days); or Group B (3 g of placebo herb). A total of 68 patients (Group A 36, Group B 32) completed the trial. The increase of functional independence measure scale score between baseline and week 4 was 24.53 ± 23.40, and between baseline and week 12 was 34.69 ± 28.89, in the Group A was greater than 11.97 ± 11.48 and 23.94 ± 14.8 in the Group B (bothP0.05). The increase of Glasgow outcome scale score between baseline and week 12 was 0.75 ± 0.77 in the Group A was greater than 0.41 ± 0.50 in the Group B (P<0.05). The results are preliminary and need a larger study to assess the efficacy of AM after stroke.

Funder

Department of Health

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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