Effect of Modified Pulsatilla Powder on Enterotoxigenic Escherichia coli O101-Induced Diarrhea in Mice

Author:

Yu Jiankang1,Zhang Yuetian1,Song Xu1,Yang Yi1,Jia Renyong1,Chen Xu1,Sun Kai1,Li Li1,Zhao Xinghong1,Cui Qiankun1,Fu Qiuting1,Zou Yuanfeng1,Li Lixia1,Yin Zhongqiong1ORCID

Affiliation:

1. Natural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China

Abstract

MPP can be effective in the treatment of E. coli O101-induced diarrhea in mice. MPP can improve the weight loss caused by diarrhea, increase spleen and thymus indices, and reduce the diarrhea index. MPP can reduce the number of WBC, regulate the level of cytokines, and regulate the intestinal microbial flora. These data suggest that MPP is a promising candidate for treatment of E. coli-induced diarrhea in humans and animals.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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