Chemical Composition andIn VitroAntioxidant, Cytotoxic, Antimicrobial, and Larvicidal Activities of the Essential Oil ofMentha piperitaL. (Lamiaceae)

Abstract

The essential oil was obtained by hydrodistillation and the identification and quantification of components were achieved with the use of GC-MS analysis. The antioxidant activity was evaluated by the method of sequestration of DPPH. Essential oils were used for study the cytotoxic front larvae ofArtemia salina. In the evaluation of the antimicrobial activity of essential oils, we employed the disk-diffusion method. The potential larvicide in mosquito larvae of the third stage of development ofAedes aegyptito different concentrations of essential oils was evaluated. The major compounds found in the essential oils ofM. piperitawere linalool (51.8%) and epoxyocimene (19.3%). The percentage of antioxidant activity was79.9±1.6%. The essential oil showed LC50= 414.6 μg/mL front ofA. salineand is considered highly toxic. It shows sensitivity and halos significant inhibition againstE. coli. The essential possessed partial larvicidal efficiency againstA. aegypti.