Depth Attenuation Degree Based Visualization for Cardiac Ischemic Electrophysiological Feature Exploration

Author:

Yang Fei1ORCID,Zhang Lei2ORCID,Lu Weigang3ORCID,Liu Lei4,Zhang Yue5ORCID,Zuo Wangmeng5,Wang Kuanquan5ORCID,Zhang Henggui56

Affiliation:

1. School of Mechanical, Electrical & Information Engineering, Shandong University, Weihai 264200, China

2. School of Art and Design, Harbin University, Harbin 150086, China

3. Department of Educational Technology, Ocean University of China, Qingdao 266100, China

4. Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190, China

5. School of Computer Science and Technology, Harbin Institute of Technology, Harbin 150001, China

6. School of Physics and Astronomy, University of Manchester, Manchester M139PL, UK

Abstract

Although heart researches and acquirement of clinical and experimental data are progressively open to public use, cardiac biophysical functions are still not well understood. Due to the complex and fine structures of the heart, cardiac electrophysiological features of interest may be occluded when there is a necessity to demonstrate cardiac electrophysiological behaviors. To investigate cardiac abnormal electrophysiological features under the pathological condition, in this paper, we implement a human cardiac ischemic model and acquire the electrophysiological data of excitation propagation. A visualization framework is then proposed which integrates a novel depth weighted optic attenuation model into the pathological electrophysiological model. The hidden feature of interest in pathological tissue can be revealed from sophisticated overlapping biophysical information. Experiment results verify the effectiveness of the proposed method for intuitively exploring and inspecting cardiac electrophysiological activities, which is fundamental in analyzing and explaining biophysical mechanisms of cardiac functions for doctors and medical staff.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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