Crystallinity and Reinforcement in Poly-L-Lactic Acid Scaffold Induced by Carbon Nanotubes

Author:

Wang Guoyong1,Qi Fangwei1,Yang Wenjing1,Yang Youwen1,He Chongxian1,Peng Shuping23ORCID,Shuai Cijun14ORCID

Affiliation:

1. Jiangxi University of Science and Technology, Ganzhou 341000, China

2. NHC Key Laboratory of Carcinogenesis and The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Xiangya Hospital, Central South University, Changsha, Hunan, China

3. Cancer Research Institute, School of Basic Medical Sciences, Central South University, Changsha, Hunan, China

4. State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China

Abstract

Poly-L-Lactic Acid (PLLA) is a bioabsorbable implant material due to its favorable biocompatibility and inherent degradability, while the insufficient mechanical strength hinders its further bone repair application. In present work, carbon nanotubes (CNTs) were introduced into PLLA scaffolds fabricated via selective laser sintering. It was found that the crystallinity of PLLA increased considerably since CNTs could promote the orderly stacking of its molecular chains, thereby improving the mechanical strength of PLLA scaffold. Furthermore, the fracture surface analysis revealed that CNTs acted as a bridge across the cracks and hindered their further expansion. Moreover, CNTs pulled out from the matrix to consume a large amount of fracture energy, which enhanced the resistance to external forces. As a consequence, the compressive strength, Vickers hardness and tensile strength of the scaffold were enhanced by 22.7%, 58.8% and 17.6%, respectively. Besides, the cells exhibited good attachment, spreading and proliferation on the scaffold. This study demonstrated that PLLA/CNTs scaffold was a promising candidate as bone implant.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Polymers and Plastics,Organic Chemistry,General Chemical Engineering

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