The Memories of NK Cells: Innate-Adaptive Immune Intrinsic Crosstalk

Author:

Gabrielli Sara1ORCID,Ortolani Claudio1,del Zotto Genny2,Luchetti Francesca1,Canonico Barbara1,Buccella Flavia1ORCID,Artico Marco3,Papa Stefano1,Zamai Loris14ORCID

Affiliation:

1. Department of Biomolecular Sciences, University of Urbino “Carlo Bo”, Urbino, Italy

2. IRCCS Istituto Giannina Gaslini, Genova, Italy

3. Department of Sensory Organs, University of Rome La Sapienza, Italy

4. Gran Sasso National Laboratory, INFN, Assergi, L’Aquila, Italy

Abstract

Although NK cells are considered part of the innate immune system, a series of evidences has demonstrated that they possess characteristics typical of the adaptive immune system. These NK adaptive features, in particular their memory-like functions, are discussed from an ontogenetic and evolutionary point of view.

Publisher

Hindawi Limited

Subject

Immunology,General Medicine,Immunology and Allergy

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