Novel Synthesis and Characterization of Thiosemicarbazone Compounds Containing 4-Acyl-2-pyrazolin-5-ones-Reference-Cited by-同舟云学术

Novel Synthesis and Characterization of Thiosemicarbazone Compounds Containing 4-Acyl-2-pyrazolin-5-ones

Published:2009 Issue:3 Volume:6 Page:747-752
ISSN:0973-4945
Container-title:E-Journal of Chemistry
language:en
Short-container-title:E-Journal of Chemistry

Author:

Rana Arjun K.¹,Parekh Nayan R.¹²,Dabhi Harish R.¹,Nadkarni Sunil S.²

Affiliation:

1. Navajivan Science College, Dahod, Gujarat University, Ahmedabad, Gujarat, India

2. Torrent Research Centre Village Bhat, Gandhinagar, Ahmedabad, Gujarat, India

Abstract

A novel synthesis of 4-acylthiosemicarbazone-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one by condensation of 4-acyl-3-methyl-1-(4`-methylphenyl)-2-pyrazolin-5-one with thiosemicarbazide is carried out. The compounds were characterized on the basis of elemental analysis, IR,1H NMR, Mass, DSC and13C NMR spectral data. The structures were investigated for their antibacterial and antifungal activity. They are very essential to study on cerebral infarction (Free radical scavenger). A single crystal X-ray study of this thiosemicarbazones and their metal complexes is in progress.

Publisher

Hindawi Limited

Subject

General Chemistry

Link

http://downloads.hindawi.com/journals/jchem/2009/472530.pdf

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