Ultrasound Elastography under Deep Learning Algorithm to Analyze the Therapeutic Effect of Clustered Regularly Interspaced Short Palindromic Repeats Short Hairpin Ribonucleic Acid Nanoparticles on Cervical Cancer

Abstract

This study aimed to analyze the effect of the deep learning algorithm on ultrasound elastography on the treatment of cervical cancer with clustered regularly interspaced short palindromic repeats (CRISPR) short hairpin ribonucleic acid (shRNA) nanoparticles, aiming to provide a reference for the clinical application of deep learning to analyze the therapeutic effect of the disease. In this study, CRISPR and shRNA plasmid nanoparticle drugs were used to treat 55 patients with cervical cancer in the experimental group, and normal saline was injected to another 53 patients in the control group, so compare the effect of nanoparticles in the treatment of cervical cancer. Professional doctors and the recurrent neural network (RNN) intelligent algorithm were used to score cervical cancer based on the ultrasound elastograph images by taking blue, green, and red (BGR) as diagnosis criteria. As a result, the experimental group had a total of 217 points before drug administration and a total of 224 points after drug administration. Each patient had an average increase of 0.13 points. The control group had a total of 200 points before drug administration and a total of 223 points after drug administration, and each patient had an average increase of 0.43 points. The experimental group was obviously different from the control group ( $P<0.05$ ). Each tissue image output by the RNN was clearer than the original image, and the score given by intelligent calculation was faster than that of professional doctors. The monitoring effect of the deep learning RNN intelligent algorithm on the therapeutic effect of nanomedicine was analyzed. It was found that the average accuracy of the experimental group and the control group was 98.95% and 90.34%, respectively; and the experimental group was greatly different from the control group ( $P<0.05$ ). In short, nano-CRISPR and shRNA drugs had remarkable effects on the treatment of cervical cancer, and the scores given by the deep learning intelligent algorithm were faster and more accurate, which provided theoretical guidance for the clinical application of deep learning algorithms to analyze the treatment effects of diseases.