Affiliation:
1. Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Centre, Suita, Japan
Abstract
Calcium channel blocker- (CCB-) associated peripheral edema does not resolve without CCB discontinuation or dose reduction. However, renin–angiotensin system (RAS) inhibitors have been reported to be effective for CCB-associated edema. We report a case of vasospastic angina with refractory CCB-associated edema. A 78-year-old man had refractory edema induced by a CCB. It was successfully treated with tolvaptan, an active vasopressin V2 receptor antagonist. The aim of this case report is to understand the mechanism and treatment of CCB-associated peripheral edema and how tolvaptan affects peripheral edema.
Funder
Japan Society for the Promotion of Science
Subject
Cardiology and Cardiovascular Medicine
Cited by
1 articles.
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