Computerized cyclic voltammetric detection after HPLC of the antineoplastic agents etoposide, teniposide, adriamycin and its metabolite adriamycinol in urine samples-Reference-Cited by-同舟云学术

Computerized cyclic voltammetric detection after HPLC of the antineoplastic agents etoposide, teniposide, adriamycin and its metabolite adriamycinol in urine samples

Published:1989 Issue:3 Volume:11 Page:106-112
ISSN:0142-0453
Container-title:Journal of Automatic Chemistry
language:en
Short-container-title:Journal of Automatic Chemistry

Author:

Ploegmakers H. H. J. L.¹,Moritz P. A.¹,Toll P. J. M. M.²,van Oort W. J.¹

Affiliation:

1. Department of Analytical Pharmacy, State University of Utrecht, Catharijnesingel 60, Utrecht 3511 GH, The Netherlands

2. Groot Ziekengasthuis Hospital, Nieuwstraat 34, 's-Hertogenbosch 5211 NL, The Netherlands

Abstract

Based on their concentrations in urine, the oxidative cyclic voltammetric mode, using a glassy carbon electrode, permits the determination of etoposide and teniposide, whereas the reductive cyclic voltammetric mode, with a static mercury drop electrode, permits the determination of adriamycin and its metabolite adriamycinol.

Publisher

Hindawi Limited

Subject

Clinical Biochemistry

Link

http://downloads.hindawi.com/journals/jamc/1989/850895.pdf

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