Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus

Author:

Gong Guowei1,Zheng Yuzhong2ORCID,Yang Yang1,Sui Yixuan3,Wen Zhen4

Affiliation:

1. Department of Bioengineering, Zunyi Medical University, Zhuhai Campus, Zhuhai, Guangdong 519041, China

2. Guangdong Key Laboratory for Functional Substances in Medicinal Edible Resources and Healthcare Products, School of Life Sciences and Food Engineering, Hanshan Normal University, Chaozhou, Guangdong 521041, China

3. Department of Neuroscience, City University of Hong Kong, Hong Kong 999077, China

4. College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China

Abstract

Astragalus is a popular Materia Medica in China, and it could be applied in the treatment of various diseases. It contains a variety of chemically active ingredients, such as saponins, flavonoids, and polysaccharides. Plant-derived bioactive chemicals are considered natural, safe, and beneficial. Among the infinite plant-identified and isolated molecules, flavonoids have been reported to have positive effects on human health. Calycosin is the most important active flavonoid substance identified predominantly within this medicinal plant. In recent years, calycosin has been reported to have anticancer, antioxidative, immune-modulatory, and estrogenic-like properties. This review collected recent relevant literatures on calycosin and summarized its potential pharmaceutical properties and working mechanism involved, which provided solid basis for future clinical research.

Funder

Natural Science Foundation of Guizhou Province

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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