Use of Continuous Intravenous Anakinra Infusion in Multisystem Inflammatory Syndrome in Children

Author:

Alolayan Abdulaziz1ORCID,Aldamegh Abdullah S.2,Alkhayrat Azzah1

Affiliation:

1. Pharmacy Department, Prince Sultan Military Medical City, Saudi Arabia

2. Pediatrics Department, Unaizah College of Medicine and Medical Sciences, Al-Qassim University, Saudi Arabia

Abstract

Coronavirus disease (COVID-19) is an emergency pandemic with a high mortality rate worldwide. One of its complications in children is developing multisystemic inflammatory syndrome related to cytokine storm. Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist used to suppress the exaggerated inflammatory response in such conditions, and it is potentially lifesaving in a cytokine storm. We present the case of a patient with critical COVID-19 associated with multisystem inflammatory syndrome in children (MIS-C) successfully treated with anakinra intravenous (IV) infusion.

Funder

Prince Sultan Military Medical City

Publisher

Hindawi Limited

Subject

Critical Care and Intensive Care Medicine

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