Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms-Reference-Cited by-同舟云学术

Progressive Resistance Exercise and Parkinson's Disease: A Review of Potential Mechanisms

Published:2012 Issue: Volume:2012 Page:1-10
ISSN:2090-8083
Container-title:Parkinson's Disease
language:en
Short-container-title:Parkinson's Disease

Author:

David Fabian J.¹^ORCID,Rafferty Miriam R.²^ORCID,Robichaud Julie A.¹,Prodoehl Janey¹,Kohrt Wendy M.³,Vaillancourt David E.⁴⁵,Corcos Daniel M.¹⁶⁷⁸

Affiliation:

1. Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA

2. Graduate Program in Neuroscience, University of Illinois at Chicago, Chicago, IL 60612, USA

3. Division of Geriatric Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA

4. Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32611, USA

5. Department of Neurology, University of Florida, Gainesville, FL 32610, USA

6. Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60612, USA

7. Department of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA

8. Department of Neurological Sciences, Rush University, Chicago, IL 60612, USA

Abstract

This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle weakness, highlights findings related to the central changes that accompany PRE in healthy individuals, and extends these findings to individuals with PD. It then illustrates the hypothesized positive effects of PRE on nigro-striatal-thalamo-cortical activation and connectivity. Second, it reviews recent findings of the use of PRE in individuals with PD. Finally, knowledge gaps of using PRE on individuals with PD are discussed along with suggestions for future research.

Funder

National Institutes of Health

Publisher

Hindawi Limited

Subject

Psychiatry and Mental health,Clinical Neurology,Neuroscience (miscellaneous)

Link

http://downloads.hindawi.com/journals/pd/2012/124527.pdf

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