The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study

Author:

Chien Kai-Ting1,Chen Ching-Chen2,Chu Chien-Ming3,Chan Ya-Lin4,Chung Hsiu-Yun4,Chang Ting-Kuo5ORCID

Affiliation:

1. Department of Orthopaedic Surgery, Mackay Memorial Hospital, Taipei, Taiwan

2. L.D.Y. Clinic of Chinese Medicine, New Taipei City, Taiwan

3. Biomedical Development Center, Mackay Memorial Hospital, Taipei, Taiwan

4. Animal Centre, Mackay Memorial Hospital, Taipei, Taiwan

5. Department of Orthopedic Surgery, Mackay Memorial Hospital, Taipei, Taiwan

Abstract

Objectives. To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. Methods. 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group’s mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported. Conclusions. The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats.

Publisher

Hindawi Limited

Subject

Applied Mathematics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modeling and Simulation,General Medicine

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