Incidence, Characteristics, and Management of Patients with Recurrent Myocardial Infarctions: Insights from the EYESHOT POST-MI

Author:

De Luca Leonardo1ORCID,Colivicchi Furio2,Gabrielli Domenico1,Lucci Donata3,Grippo Gabriele4,Piemonte Francesco5,Villari Bruno6,Di Lenarda Andrea7,Oliva Fabrizio8,Gulizia Michele Massimo9

Affiliation:

1. Department of Cardiosciences, Division of Cardiology, A.O. San Camillo-Forlanini, Roma, Italy

2. Division of Cardiology, S. Filippo Neri Hospital, Roma, Italy

3. ANMCO Research Center, Heart Care Foundation, Firenze, Italy

4. Division of Cardiology, Nuovo Ospedale, Prato, Italy

5. Division of Cardiology, San Giovanni di Dio Hospital, Frattamaggiore (NA), Italy

6. Division of Cardiology, Ospedale Fatebenefratelli, Benevento, Italy

7. Division of Cardiology, Azienda Sanitaria Universitaria Integrata di Trieste, Trieste, Italy

8. Cardiac Intensive Care Unit and De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy

9. Division of Cardiology, Garibaldi-Nesima Hospital, Catania, Italy

Abstract

Background. It is unknown whether patients who survived two or multiple episodes of myocardial infarction (MI) present different clinical characteristics and management than patients at their first MI. Methods. The EYESHOT post-MI was a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event. In 3 months of enrolment, 165 Italian cardiology centers included 1633 consecutive post-MI patients. In the present analysis, we stratified the study cohort according to the number of prior MI episodes (i.e., 1, 2 or ≥3). Results. Among the 1618 patients enrolled with complete data on MI history, 1335 (82.5%) were at their first MI episode, 209 (12.9%) had a history of 2 MIs, and the remaining 74 (4.6%) had ≥ 3 prior MIs. Patients with a history of multiple MIs were increasingly older and presented a significantly higher rate of risk factors compared to those at their first MI. During the year prior to enrolment, patients with 2 or ≥3 MI episodes more frequently underwent coronary angiography compared to the other group ( p < 0.0001 ). In addition, several lifesaving and antianginal drugs were more frequently prescribed in patients presenting with a history of multiple MIs compared to those at their first MI. Conclusions. Our data suggest that patients with multiple MIs managed by cardiologists in routine clinical practice present an incremental clinical risk, more frequently undergo coronary angiography, and are more intensively managed with pharmacological therapies compared to patients at their first MI episode.

Publisher

Hindawi Limited

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging

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