Biosynthesis of Biocompatible AgNPs Using Medicinally Important Carduus edelbergii Rech.f. Extract for Multifarious Biological Activities

Author:

Jamil Shahid1ORCID,Dastagir Ghulam1ORCID,Foudah Ahmed Ibrahim2ORCID,Alqarni Mohammad Hamed2ORCID,Yusufoglu Hasan Soliman3ORCID,Alkreathy Huda Mohammed4ORCID,Erturk Omer5ORCID,Khan Rahmat Ali6ORCID,Shah Muhammad Abdur Rehman6ORCID

Affiliation:

1. Department of Botany, University of Peshawar, KPK, Pakistan

2. Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia

3. Department of Pharmacognosy & Pharmaceutical Chemistry, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah 51418, Saudi Arabia

4. Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

5. Ordu University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Ordu, Turkey

6. Department of Biotechnology, University of Science and Technology Bannu, KPK, Pakistan

Abstract

In current scenario, plant-mediated synthesis of nanoparticles has received significant interest owing to its cost-effectiveness and eco-friendly methods. This study was planned to find the potential of Carduus edelbergii Rech.f. extract for the fabrication of silver nanoparticles (AgNPs) and their subsequent antibacterial, antifungal, cytotoxic, and antioxidant activities. The prepared plant extract was analyzed for phytochemicals, elements, and nutrients. The fabricated AgNPs were characterized by spectroscopy (UV-Vis), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The synthesized AgNPs and the Carduus edelbergii extract were investigated for their antioxidant, antibacterial, cytotoxic, and antifungal characteristics. The results showed that the plant extract contains a wide range of important nutrients and secondary metabolites. The synthesized AgNPs were crystalline and globular with an average diameter of 36.5 nm and exhibited a localized surface plasmon resonance (LSPR) peak at roughly 420 nm. As compared to Carduus edelbergii extract, the phytofabricated AgNPs had an increased antioxidant and cytotoxic efficacy. The AgNPs showed substantial antibacterial action against Gram-positive (Staphylococcus epidermis and Staphylococcus aureus) and Gram-negative (Klebsiella aerogenes and Escherichia coli) bacteria. The findings revealed that the phytofabricated AgNPs could be an effective antioxidant, antibacterial, and antifungal for treatment of medical conditions.

Publisher

Hindawi Limited

Subject

General Materials Science

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3