Conversion of Aquaculture Waste into Biomedical Wealth: Chitin and Chitosan Journey

Author:

Joseph Jerrine1,Manigundan Kaari1,Shamya Arokia Rajan Mary1,Radhakrishnan Manikkam1,Gopikrishnan Venugopal1,Kumaran Subramanian1ORCID,Thirunavukkarasu Rajasekar1,Aruni Wilson23,Shanmugam Velmurugan4ORCID

Affiliation:

1. Centre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India

2. Musculoskeletal Disease Research Laboratory US Department of Veteran Affairs, Loma Linda, CA, USA

3. Amity University, Mumbai, Maharashtra, India

4. Department of Biology, School of Natural Science, Madawalabu University, Oromia Region, Ethiopia

Abstract

Biowaste originating from aquaculture sector represents a potential feedstock to produce value-added substances and materials like chitin and chitosan. They are the long chain polymers of N-acetylglucosamine polymers with huge industrial and biomedical significance. Chitin has long been recognized as a useful biomaterial for drug delivery and neurological therapy. Similarly, chitosan oligosaccharide, a short chain polymer derived from chitin/chitosan, has been identified for its potential biomedical applications, including antibacterial, anti-inflammatory, and anti-Alzheimer action. Chitosan nanoparticles are also used extensively in biomedical applications. Here we have critically summarized various methods for the extraction of chitin, chitosan, and chitooligossacharides and chitosan nanoparticle preparation and their diverse biomedical applications.

Funder

Madawalabu University

Publisher

Hindawi Limited

Subject

General Engineering,General Materials Science

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