Intestinal Diffuse Large B-Cell Lymphoma in a Patient with Systemic Lupus Erythematosus

Author:

Iwamuro Masaya1ORCID,Takahashi Takahide2,Ota Yoko3,Tanaka Takehiro4,Asada Noboru5,Yano Shuya6,Uka Mayu7,Nakamura Rei8,Baba Yuki1,Kawano Seiji1ORCID,Kawahara Yoshiro9,Okada Hiroyuki1

Affiliation:

1. Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan

2. Division of Medical Support, Okayama University Hospital, Okayama 700-8558, Japan

3. Department of Pathology & Experimental Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan

4. Department of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan

5. Department of Hematology and Oncology, Okayama University Hospital, Okayama 700-8558, Japan

6. Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan

7. Department of Radiology, Okayama University Hospital, Okayama 700-8558, Japan

8. Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, Japan

9. Department of Practical Gastrointestinal Endoscopy, Okayama University Hospital, Okayama 700-8558, Japan

Abstract

A 44-year-old Japanese woman with systemic lupus erythematosus (SLE) presented to our hospital with abdominal pain. Radiological and endoscopic examinations led to the diagnosis of diffuse large B-cell lymphoma of the jejunum, which was subsequently resected. Patients with SLE reportedly have an increased risk of non-Hodgkin lymphoma, as demonstrated by our patient. Hence, lymphoma should be considered in the differential diagnosis of neoplastic lesions emerging in SLE patients. In addition, flow cytometry using endoscopically biopsied fragments is useful for the immediate diagnosis of lymphoma, leading to timely and accurate preoperative staging.

Publisher

Hindawi Limited

Subject

General Engineering

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