Chemical Constituents and Insecticidal Activities of the Essential Oil ofCinnamomum camphoraLeaves againstLasioderma serricorne

Author:

Chen Hai Ping12,Yang Kai1,You Chun Xue1,Lei Ning3,Sun Rui Qi4,Geng Zhu Feng4,Ma Ping3,Cai Qian2,Du Shu Shan1,Deng Zhi Wei4

Affiliation:

1. Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, China

2. College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, Liaoning 116600, China

3. Department of Pharmacy, General Hospital of Second Artillery, PLA, Haidian District, Beijing 100088, China

4. Analytical and Testing Center, Beijing Normal University, Beijing 100875, China

Abstract

During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil ofCinnamomum camphoraleaves was found to possess strong fumigant and contact toxicity againstLasioderma serricorneadults with LC50/LD50values of 2.5 mg/L air and 21.25 μg/adult, respectively. The essential oil obtained by hydrodistillation was investigated by GC and GC-MS. The main components of the essential oil were identified to beD-camphor (40.54%), linalool (22.92%), cineole (11.26%), and 3,7,11-trimethyl-3-hydroxy-6,10-dodecadien-1-yl acetate (4.50%). Bioactivity-directed chromatographic separation on repeated silica gel columns led to the isolation ofD-camphor and linalool.D-camphor and linalool showed strong fumigant toxicity (LC50= 2.36 and 18.04 mg/L air, resp.) and contact toxicity (LD50= 13.44 and 12.74 μg/adult, resp.) againstL. serricorne. The results indicate that the essential oil ofC. camphoraand its active compounds had the potential to be developed as natural fumigants and insecticides for control ofL. serricorne.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

General Chemistry

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