A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2

Author:

Bangolo Ayrton I.1ORCID,Akhter Mahabuba1,Auda Auda1,Akram Rahina1,Nagesh Vignesh K.1,Athem Donnee1,Thomas Reenu1,Tibalan Ligaya1,Trivedi Mansi1,Mushtaq Saima1,Singh Neha1,Bagale Pracheta1,Arana Georgemar V.1,Khan Tayyaba1,Sharma Shelja1,Mynedi Swetha1,Patel Dhara D.1,Saini Mandeep1,Chinthakuntla Madhurya R.1,Ahmed Kareem2,Gad Mary1,Gondhi Srikara Dheer D. R.1,Arana Georgemar1,Gurumoorthy Rohini B.1,Weissman Simcha1ORCID

Affiliation:

1. Department of Internal Medicine, Palisades Medical Center, North Bergen, NJ, USA

2. Department of Internal Medicine, University of Washington, Seattle, Washington, USA

Abstract

Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute pancreatitis following the Pfizer-BioNTech COVID-19 mRNA vaccine. To our knowledge, no cases of acute pancreatitis have been yet reported following the Johnson & Johnson’s Janssen COVID-19 vaccine (J& J vaccine). Herein we report a 34-year-old male with no significant past medical history admitted with acute necrotizing pancreatitis, the day following the receipt of the J&J vaccine. Based on the Naranjo and the modified Naranjo scale, the patient met the requirements for probable drug induced pancreatitis. This case report has the objective to raise awareness of a potentially severe side effect of the J&J vaccine. We hope to use this case to support screening all patients for previous history of acute pancreatitis before administration of the J& J vaccine.

Publisher

Hindawi Limited

Subject

General Medicine

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