Atypical Presentation of Amyloidosis in a Female Patient with Muscle Weakness

Author:

Lashkari Raziyeh1,Loghman Maryam2,Aghaghazvini Leila3,Saffar Hiva4,Ziaadini Bentolhoda5,Shahriarirad Reza67ORCID,Nekooeian Mohammad89,Nejadhosseinian Mohammad1011,Alikhani Majid2ORCID

Affiliation:

1. Semnan University of Medical Sciences, Semnan, Iran

2. Department of Internal Medicine, School of Medicine, Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

3. Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

4. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

5. Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran

6. School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

7. Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

8. Health and System Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

9. Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

10. Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran

11. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Muscle involvement represents a well-recognized but rare manifestation of amyloidosis. Here, we report a 40-year-old female who presented with muscle weakness, musculoskeletal pain, and proteinuria, which was eventually diagnosed as myopathic amyloidosis based on muscle biopsy results. A multidisciplinary approach appears to be the cornerstone of the diagnostic work up for recognizing the unusual amyloid myopathy.

Publisher

Hindawi Limited

Subject

General Medicine

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