Silver Binding Nucleolar Organizer Regions Dots in Oral Leukoplakia with Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An In Vivo Study-Reference-Cited by-同舟云学术

Silver Binding Nucleolar Organizer Regions Dots in Oral Leukoplakia with Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An In Vivo Study

Published:2014-04-30 Issue: Volume:2014 Page:1-4
ISSN:2090-438X
Container-title:ISRN Dentistry
language:en
Short-container-title:ISRN Dentistry

Author:

Mansoor Samadi Fahad¹,Thattil Sebastian Bastain²,Singh Anil³,Chandra Shaleen¹^ORCID,Mohammad Shadab⁴,Singh Arun⁵,Halappa Thippeswamy⁶,Samadi Firoza⁷

Affiliation:

1. Department of Oral Pathology & Microbiology, King George's Medical University, Lucknow, India

2. Department of Oral Pathology & Microbiology, Mahe Institute of Dental Sciences, Palloor, Mahe, Puducherry, India

3. Department of Oral Pathology & Microbiology, Saraswati Dental College, Lucknow, India

4. Department of Oral & Maxillofacial Surgery, King George's Medical University, Lucknow, India

5. Department of Oral Pathology & Microbiology, Kothiwal Dental College & Research Centre, Moradabad, Uttar Pradesh, India

6. Department of Oral Pathology & Microbiology, Babu Banarsi Das College of Dental Sciences, Lucknow, India

7. Department of Pedodontics, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India

Abstract

Silver binding nucleolar organizer regions (AgNOR) in normal oral mucosa (NOM), oral leukoplakia with epithelial dysplasia (ED), and oral squamous cell carcinoma (OSCC) were studied. The mean AgNOR count per nucleus increased from NOM to ED to OSCC. Tissue showing ED in oral leukoplakia and OSCC cases showed higher counts, wider scatter, and smaller size of AgNOR dots in the nuclei. The study seems to suggest that time method has some potential in distinguishing between NOM and oral leukoplakia with ED and OSCC. Studies of larger numbers are needed to arrive at more substantial conclusions.

Publisher

Hindawi Limited

Subject

Management of Technology and Innovation

Link

http://downloads.hindawi.com/archive/2014/479187.pdf

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