Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety-Reference-Cited by-同舟云学术

Synthesis and Antimicrobial Activity of Carbohydrate Based Schiff Bases: Importance of Sugar Moiety

Published:2013-12-12 Issue: Volume:2013 Page:1-5
ISSN:1687-9341
Container-title:International Journal of Carbohydrate Chemistry
language:en
Short-container-title:International Journal of Carbohydrate Chemistry

Author:

Appelt Helmoz R.¹,Oliveira Julieta S.²,Santos Roberto C. V.³,Rodrigues Oscar E. D.⁴,Santos Maura Z.³,Heck Elisiane F.³,Rosa Líria C.³

Affiliation:

1. Campus São Gabriel, Universidade Federal do Pampa, Avenida Antônio Trilha 1847, 97300-000 São Gabriel, RS, Brazil

2. Campus Cerro Largo, Universidade Federal da Fronteira Sul, R. Major Antônio Cardoso 590, 97900-000 Cerro Largo, RS, Brazil

3. Ciências da Saúde, Centro Universitário Franciscano, Rua dos Andradas 1614-Centro, -97010-032 Santa Maria, RS, Brazil

4. Departamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil

Abstract

A series of D-glucosamine derivatives were synthesized (2–4) and evaluated for their antimicrobial activity. Some of the compounds investigated have shown significant antimicrobial activity against Gram-positive and Gram-negative bacterial strains as well as a few fungal strains. The results suggest that the presence of sugar moiety is necessary to biological activity.

Publisher

Hindawi Limited

Link

http://downloads.hindawi.com/archive/2013/320892.pdf

Reference28 articles.

1. Potencialidades e oportunidades na química da sacarose e outros açúcares

2. Carbohydrate derivative ligands in asymmetric catalysis

3. Ligands Derived from Carbohydrates for Asymmetric Catalysis

4. Use of sugar-based ligands in selective catalysis: Recent developments

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