High Transmission Rates of Early Omicron Subvariant BA.2 in Bangkok, Thailand

Author:

Petcharat Sininat1ORCID,Supataragul Ananporn1ORCID,Hirunpatrawong Piyapha2ORCID,Torvorapanit Pattama13ORCID,Klungthong Chonticha4ORCID,Chinnawirotpisan Piyawan4ORCID,Ninwattana Sasiprapa12ORCID,Thippamom Nattakarn1ORCID,Paitoonpong Leilani13ORCID,Suwanpimolkul Gompol13ORCID,Jantarabenjakul Watsamon13ORCID,Buathong Rome5ORCID,Joonlasak Khajohn4ORCID,Manasatienkij Wudtichai4ORCID,Rattanatumhi Khwankamon1ORCID,Chantasrisawad Napaporn13ORCID,Chumpa Nuntana13ORCID,Cotrone Thomas S.4ORCID,Fernandez Stefan4ORCID,Sriswasdi Sira67ORCID,Wacharapluesadee Supaporn1ORCID,Putcharoen Opass13ORCID

Affiliation:

1. Thai Red Cross Emerging Infectious Diseases Clinical Center, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand

2. Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand

3. Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand

4. Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand

5. Department of Disease Control, Ministry of Public Health, Muang, Nonthaburi 11000, Thailand

6. Center of Excellence in Computational Molecular Biology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand

7. Center for Artificial Intelligence in Medicine, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand

Abstract

The emergence of Omicron as the fifth variant of concern within the SARS-CoV-2 pandemic in late 2021, characterized by its rapid transmission and distinct spike gene mutations, underscored the pressing need for cost-effective and efficient methods to detect viral variants, especially given their evolving nature. This study sought to address this need by assessing the effectiveness of two SARS-CoV-2 variant classification platforms based on RT-PCR and mass spectrometry. The primary aim was to differentiate between Delta, Omicron BA.1, and Omicron BA.2 variants using 618 COVID-19-positive samples collected from Bangkok patients between November 2011 and March 2022. The analysis revealed that both BA.1 and BA.2 variants exhibited significantly higher transmission rates, up to 2-3 times, when compared to the Delta variant. This research presents a cost-efficient approach to virus surveillance, enabling a quantitative evaluation of variant-specific public health implications, crucial for informing and adapting public health strategies.

Funder

King Chulalongkorn Memorial Hospital

Publisher

Hindawi Limited

Subject

Infectious Diseases,Virology

Reference25 articles.

1. Classification of omicron (B.1.1.529): SARS-CoV-2 variant of concern;World Health Organization,2021

2. Characterization of the novel SARS‐CoV‐2 Omicron (B.1.1.529) variant of concern and its global perspective

3. Tracking SARS-CoV-2 variants;World Health Organization,2022

4. Emergence of Omicron third lineage BA.3 and its importance

5. Sequence analysis of the emerging SARS‐CoV‐2 variant Omicron in South Africa

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