Cutaneous Vasculitis, Interstitial Pneumonia with Crazy-Paving Appearance, and Positive pANCA in a Patient with Severe Crohn’s Disease

Author:

Chen Guang-liang12,Wang Juan3,Li Bao-zhen1ORCID,Li Li-mei1,Mo Han-you1,Ye Shuang4

Affiliation:

1. Department of Rheumatology & Immunology, Affiliated Hospital of Guilin Medical University, 5th Floor, Building No. 3, 15 Lequn Road, Guilin 541001, China

2. Department of Internal Medicine 3, University of Erlangen-Nuremberg, 91054 Erlangen, Germany

3. Department of Rheumatology, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China

4. Department of Rheumatology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 145 Shandong C Road, Shanghai 200001, China

Abstract

Cutaneous vasculitis, interstitial pneumonia with crazy-paving appearance on high-resolution computed tomography, and repeated positive perinuclear anti-neutrophil cytoplasmic antibodies (pANCA) are rarely found together in patients with inflammatory bowel disease in the existing literature. We report the case of a Chinese patient previously diagnosed with cutaneous vasculitis and interstitial pneumonia, who presented with acute pain and mass in his right lower quadrant a couple of years later. The terminal ileum biopsy and postoperative pathology confirmed Crohn’s disease (CD).

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

General Engineering

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