Clinical Effect and Safety Analysis of 2.5 μg/kg DEX Nasal Drop in Child Undergoing Ultrasound Examination

Abstract

In order to meta-analyze the clinical effect and safety of dexmedetomidine (DEX) intranasal sedation in child ultrasound examination, literature retrieval is carried out in Wanfang Medicine, PubMed database, domestic medical research journals. The relevant medical information literature on clinical effects and safety are analyzed by using Rev Man 5.2 software. The retrieved literature is screened according to the research object, method, disease type and other criteria. The results of meta-analysis show that dexmedetomidine intranasal sedation is applied to child undergoing ultrasound examination, and the SPO2 and sedation time are significantly higher than those in the conventional sedation group (P < 0.05). The time/score is significantly lower than that in the conventional sedation group (P < 0.05), and the incidence of adverse reactions in the dexmedetomidine intranasal sedation group is significantly lower than that in the conventional sedation group (P < 0.05).