FDG-PET in Follicular Lymphoma Management

Author:

Bodet-Milin C.1,Eugène T.1,Gastinne T.2,Frampas E.3,Le Gouill S.2,Kraeber-Bodéré F.1

Affiliation:

1. Nuclear Medicine Department, University Hospital-ICO-Gauducheau, INSERM UMR 892 Team 13, 44093 Nantes, France

2. Hematology Department, University Hospital, INSERM UMR 892 Team 10, 44093 Nantes, France

3. Radiology Department, University Hospital, INSERM UMR 892 Team 13, 44093 Nantes, France

Abstract

18-Fluoro-deoxyglucose positron emission tomography/computerised tomography (FDG PET/CT) is commonly used in the management of patients with lymphomas and is recommended for both initial staging and response assessment after treatment in patients with diffuse large B-cell lymphoma and Hodgkin lymphoma. Despite the FDG avidity of follicular lymphoma (FL), FDG PET/CT is not yet applied in standard clinical practice for patients with FL. However, FDG PET/CT is more accurate than conventional imaging for initial staging, often prompting significant management change, and allows noninvasive characterization to guide assessment of high-grade transformation. For restaging, FDG PET/CT assists in distinguishing between scar tissue and viable tumors in residual masses and a positive PET after induction treatment would seem to predict a shorter progression-free survival.

Publisher

Hindawi Limited

Subject

Oncology

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