Noncoding RNAs and Virus and Treatment in Allergic Rhinitis-Reference-Cited by-同舟云学术

Noncoding RNAs and Virus and Treatment in Allergic Rhinitis

Published:2022-10-15 Issue: Volume:2022 Page:1-8
ISSN:1741-4288
Container-title:Evidence-Based Complementary and Alternative Medicine
language:en
Short-container-title:Evidence-Based Complementary and Alternative Medicine

Author:

Lei Zhu¹,Feng Guangrui²,Wang Zhiguo³,Ning Zhifeng⁴^ORCID

Affiliation:

1. Otolaryngology Department, Xianning First People’s Hospital, Xianning 437100, Hubei, China

2. Cardiovascular Medicine Department, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning 437100, Hubei, China

3. Dermatology Department, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning 437100, Hubei, China

4. Human Anatomy Department, Basic Medicine College, Hubei University of Science and Technology, Xianning 437100, Hubei, China

Abstract

Allergic rhinitis (AR) is a type I hypersensitivity reaction disease caused by inhaled allergens and immunoglobulin E (IgE)-mediated. Noncoding RNA (ncRNA) is an important regulator involved in gene expression and can be detected in the cytoplasm or extracellular fluid, which mainly includes microRNAs (miRNA, length 22–24 nucleotides), long noncoding RNAs (lncRNA, length >200 nucleotides), and circRNAs. LncRNA and miRNA both participate in the regulation of immune function. Some respiratory viral infections can aggravate allergic rhinitis, such as a respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). However, the interaction between viral infection and allergy is complex and the mechanism is still unclear. In this review, we summarized the interactions of noncoding RNAs and viruses in the occurrence and development of AR, along with the treatments focusing on the noncoding RNAs in the past five years.

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

Link

http://downloads.hindawi.com/journals/ecam/2022/1979447.pdf

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