Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries-Reference-Cited by-同舟云学术

Front-Loading Sputum Microscopy Services: An Opportunity to Optimise Smear-Based Case Detection of Tuberculosis in High Prevalence Countries

Published:2009 Issue: Volume:2009 Page:1-6
ISSN:1687-9686
Container-title:Journal of Tropical Medicine
language:en
Short-container-title:Journal of Tropical Medicine

Author:

Ramsay Andy¹²,Yassin Mohammed Ahmed¹³,Cambanis Alexis¹,Hirao Susumu¹,Almotawa Ahmad¹,Gammo Mohamed¹,Lawson Lovett⁴,Arbide Izabel⁵,Al-Aghbari Nasher⁶,Al-Sonboli Najla⁶,Sherchand Jeevan Bahadur⁷,Gauchan Punita⁷,Cuevas Luis Eduardo¹

Affiliation:

1. Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK

2. UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, World Health Organization, 1211 Geneva 27, Switzerland

3. TB and Leprosy Control Programme, Southern Region Health Bureau, P.O. Box 149, Awassa, Ethiopia

4. Zankli Medical Centre, P.O. Box 7745, Abuja, Nigeria

5. Bushullo Major Health Centre, P.O. Box 5, Awassa, Ethiopia

6. National Tuberculosis Institute, Sana'a, Yemen

7. Microbiology and Parasitology and Health Research Laboratory, Infectious and Tropical Disease Research Centre, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal P.O. Box 10404, Nepal

Abstract

Setting. Ethiopia, Nepal, Nigeria, and Yemen.Objective. To reduce the time to complete sputum microscopy.Design. Cross-sectional surveys enrolling 923 patients with chronic cough in the 4 countries and using similar protocols. Spot-morning-spot sputum specimens were collected. An additional sputum specimen (Xspot) was collected one hour after the first, and the yields of the first two or the three specimens collected as spot-morning-spot or spot-Xspot-morning were compared.Results. 216 patients had≥one positive smear. 210 (97%) were identified by the spot-morning-spot, and 210 (97%) were identified by the spot-Xspot-morning specimens, with 203 and 200 identified by the first 2 specimens of each approach, respectively. Neither difference was significant.Conclusions. The time to complete smear microscopy could be reduced.

Publisher

Hindawi Limited

Subject

General Medicine,Microbiology,Parasitology

Link

http://downloads.hindawi.com/journals/jtm/2009/398767.pdf

Reference16 articles.

1. Same-day smears in the diagnosis of tuberculosis

2. Improvement of tuberculosis case detection and reduction of discrepancies between men and women by simple sputum-submission instructions: a pragmatic randomised controlled trial

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