Biological Important Ni(II) Ternary Complexes Derived from 2-Substituted Benzothiazoles and Amino Acids

Abstract

Biological important ternary complexes of the type [NiCl(L-L) (A-A)(H2O)] and [Ni(L-L´)(A-A)(H2O)2], where A-A = Glycine (Gly), Alanine (Ala), L-L = 2-(2´-aminophenyl)benzothiazole (APBT) and L-L´ = 2-(2´-hydroxyphenyl)benzothiazole (HPBT), 2-(2´-mercaptophenyl)benzothiazole (MPBT) have been synthesized. These complexes have been characterized by elemental analysis, molecular weight determination, conductivity, magnetic measurements, infrared, electronic spectral and TGA studies. On the basis of above described studies an octahedral geometry has been suggested for these complexes. All these complexes are coloured, thermally stable, monomeric and non-electrolytic in nature. The ligands and their metal complexes were tested against pathogenic fungiAspergillus nigerandFusarium oxysporumto assess their fungicidal properties, the antifungal activity data reveals that these metal complexes are found more fungitoxic than the parent ligands.