A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms

Author:

Sato Suguru1ORCID,Morimoto Julia1,Oguchi Yasuharu2,Umeda Takashi1,Kawamata Takaya1,Rikimaru Mami1,Koizumi Tatsuhiko1,Togawa Ryuichi1,Suzuki Yasuhito1,Sato Yuki1,Uematsu Manabu1,Minemura Hiroyuki1,Nikaido Takefumi1,Fukuhara Atsuro1,Saito Junpei1ORCID,Kanazawa Kenya1,Tanino Yoshinori1ORCID,Munakata Mitsuru3,Shibata Yoko1

Affiliation:

1. Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Fukushima, Japan

2. Department of Ophthalmology, School of Medicine, Fukushima Medical University, Fukushima, Japan

3. Department of Infectious Disease and Pulmonary Medicine, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu, Japan

Abstract

We report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptoms presenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increased by the disease course of EGPA. Considering the course of clinical symptoms, there is a possibility that orbital manifestations were one of the clinical features during the disease course of EGPA while the histological features of right eyelid tissue and other ocular manifestations were consistent with the diagnosis of IgG4 related disease.

Publisher

Hindawi Limited

Subject

Immunology,Immunology and Allergy

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