Correlation between PD-L1 Expression, Clinicopathological Factors, and Metastasis Risk in Colorectal Cancer Patients-Reference-Cited by-同舟云学术

Correlation between PD-L1 Expression, Clinicopathological Factors, and Metastasis Risk in Colorectal Cancer Patients

Published:2024-01-08 Issue: Volume:2024 Page:1-5
ISSN:0961-5423
Container-title:European Journal of Cancer Care
language:en
Short-container-title:European Journal of Cancer Care

Author:

Zarbakhsh Alireza¹^ORCID,Khalaji Amirreza²³^ORCID,Vahedi Amir¹^ORCID,Dolatkhah Roya¹^ORCID,Gholami Nasrin¹^ORCID

Affiliation:

1. Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2. Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

3. Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

This study investigated the correlation between PD-L1 expression, metastasis, and survival in colorectal cancer (CRC) patients. PD-L1 expression was not significantly associated with overall survival, disease-free survival, or mortality rate. However, a significant difference was observed between PD-L1 positive and negative patients regarding the presence of metastasis, which was higher in the PD-L1 positive group. These findings suggest that PD-L1 expression may impact metastasis in CRC patients but not overall survival.

Publisher

Hindawi Limited

Link

http://downloads.hindawi.com/journals/ejcc/2024/5578953.pdf

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