Novel Study Antimicrobial and Biocompatibility Effect of Magnesium Silver Alloys 1% on Bovine Bacterial Species

Author:

Nomier Yousra12ORCID,Meiβner Jessica2ORCID,Kietzmann Manfred2

Affiliation:

1. Department of Pharmacology and Toxicology, Pharmacy College, Jazan University, Jazan, Saudi Arabia

2. Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Foundation, Hannover, Germany

Abstract

MgAg 1% alloys inhibit bacterial growth during the dry-off period. MgAg1% silver and magnesium amount was determined and the supernatant was used for the detection of antibacterial tests against S. aureus and E. coli and Geobacillus stearothermophilus var. calidolacits. The antibacterial effect of AgNO3 solution and degradation medium of MgAg1% sticks were evaluated. The bouillon dilution test showed a 5-fold reduction in bacterial colonies. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) calculations were used to test the antibacterial activity. The Brilliant Black Reduction Test (BRT-MRL screening test) showed inhibition of Geobacillus stearothermophilus bacteria at AgNO3 concentrations 0.01 mmol/l and 3 ml of degradation medium. Results were satisfying, concerning biocompatibility, degradation, and antibacterial effects.

Publisher

Hindawi Limited

Subject

General Veterinary

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