Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Author:

Yu Dengjie12,Cai Zijun12ORCID,Li Daishi3,Zhang Yi12,He Miao12,Yang Yuntao12,Liu Di12,Xie Wenqing12ORCID,Li Yusheng12ORCID,Xiao Wenfeng12ORCID

Affiliation:

1. Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China

2. National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008 Hunan, China

3. Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China

Abstract

Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.

Funder

Key program of Health Commission of Hunan Province

Publisher

Hindawi Limited

Subject

Cell Biology,Molecular Biology

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