Influence ofHelicobacter pyloriInfection on Metabolic Syndrome in Old Chinese People

Abstract

Background. H. pyloriinfection is one of the most common chronic infectious inflammatory diseases worldwide and is also a risk factor for atherosclerosis. Patients with metabolic syndrome are known to be at increased risk for atherosclerosis. The aim of our study was to assess the effects ofH. pyloriinfection on serum lipids, body mass index (BMI), and metabolic syndrome in old Chinese people.Material and Method.A total of 191 (133 males and 58 females, aged73.19±11.03years) people who had gastroscopy examination in our hospital were divided intoH. pylori-positive group (n=80) andH. pylori-negative group (n=111).H. pyloriinfection was diagnosed by rapid urease test.Results.Patients withH. pyloriinfection had higher BMI and fasting glucose levels and incidence of metabolic syndrome (p<0.01). It was found that BMI (p<0.01, OR 74.469),H. pyloriinfection (p<0.01, OR 5.427), total cholesterol (p<0.01, OR 15.544), and diabetes mellitus (p<0.01, OR 23.957) were significantly associated with the risk of metabolic syndrome by binary logistic regression analysis.Conclusions.Patients withH. pyloriinfection had higher BMI and fasting glucose levels and had incidence of metabolic syndrome.