The Effect of Pudilan Anti-Inflammatory Oral Liquid on the Treatment of Mild Recurrent Aphthous Ulcers

Author:

Jin Ying1ORCID,Lin Xiaoping1ORCID,Song Liming1ORCID,Liu Mengnan1ORCID,Zhang Ying2ORCID,Qi Xiangmin3ORCID,Zhao Danping4ORCID

Affiliation:

1. Department of Stomatology, Shengjing Hospital of China Medical University, Shenyang 110004, China

2. Stomatology Hospital of China Medical University, Shenyang 110004, China

3. School of Stomatology, Shandong University, Jinan 250015, China

4. Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China

Abstract

Recurrent aphthous ulcers are the most common recurrent oral mucosal lesions characterized by recurrence and pain. The aim of this research is to evaluate the short-term curative effect of the traditional Chinese medicine “Pudilan anti-inflammatory oral liquid” on mild recurrent aphthous ulcers. A total of 234 patients were divided into a treatment group and a control group. Both groups used vitamin B2 as the basis of treatment. The treatment group took a Pudilan anti-inflammatory oral solution for 8 days while the control group was given a liquid placebo. The ulcer size, pseudomembrane, peripheral congestion, and pain scores of the treatment group were lower than before treatment. The curative effect on the Pudilan group was statistically significant compared with the control group. The final therapeutic effect on the treatment group was better than that on the control group. The healing time of mild recurrent aphthous ulcers can be shortened by Pudilan anti-inflammatory oral liquid, and pain is relieved without adverse reactions. Pudilan provides a new reference drug for the treatment of mild recurrent oral ulcers.

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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