Atypical Nodular Pulmonary Kappa Light-Chain Deposition-Reference-Cited by-同舟云学术

Atypical Nodular Pulmonary Kappa Light-Chain Deposition

Published:2021-03-10 Issue: Volume:2021 Page:1-4
ISSN:2090-679X
Container-title:Case Reports in Pathology
language:en
Short-container-title:Case Reports in Pathology

Author:

Nellipudi Jessy¹²^ORCID,Brealey John³^ORCID,Klebe Sonja²³^ORCID,Lance David¹⁴

Affiliation:

1. Department of Cardiothoracic Surgery, Flinders Medical Centre, Southern Adelaide Local Health Network, South Australia, Australia

2. College of Medicine and Public Health, Flinders University, South Australia, Australia

3. Department of Anatomical Pathology, Flinders Medical Centre, Southern Adelaide Local Health Network, South Australia, Australia

4. Fellow of the Royal Australian College of Surgeons, Australia

Abstract

We report a case of an incidental positron emission tomography avid right middle lobe lesion which was increasing in size. Due to concerns regarding malignancy, the patient underwent right middle lobectomy. Microscopic examination showed a

12 \times 10 \times 10

mm poorly circumscribed lesion composed of eosinophilic material. The material labelled strongly for kappa light chains; however, Congo red stain was only weakly positive and without “apple-green” positive birefringence under polarised light. Electron microscopy revealed fibrillar amyloid-like material. The features were those of kappa light-chain deposition.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/journals/cripa/2021/5578885.pdf

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