Artificial Intelligence-Guided Subspace Clustering Algorithm for Glioma Images

Abstract

In order to improve the accuracy of glioma segmentation, a multimodal MRI glioma segmentation algorithm based on superpixels is proposed. Aiming at the current unsupervised feature extraction methods in MRI brain tumor segmentation that cannot adapt to the differences in brain tumor images, an MRI brain tumor segmentation method based on multimodal 3D convolutional neural networks (CNNs) feature extraction is proposed. First, the multimodal MRI is oversegmented into a series of superpixels that are uniform, compact, and exactly fit the image boundary. Then, a dynamic region merging algorithm based on sequential probability ratio hypothesis testing is applied to gradually merge the generated superpixels to form dozens of statistically significant regions. Finally, these regions are postprocessed to obtain the segmentation results of each organization of GBM. Combine 2D multimodal MRI images into 3D original features and extract features through 3D-CNNs, which is more conducive to extracting the difference information between the modalities, removing redundant interference information between the modalities, and reducing the original features at the same time. The size of the neighborhood can adapt to the difference of tumor size in different image layers of the same patient and further improve the segmentation accuracy of MRI brain tumors. The experimental results prove that it can adapt to the differences and variability between the modalities of different patients to improve the segmentation accuracy of brain tumors.