Cypermethrin-Induced Toxic Effect on Glycogen Metabolism in Estuarine Clam,Marcia Opima(Gmelin, 1791) of Ratnagiri Coast, Maharashtra

Abstract

Cypermethrin is a synthetic pyrethroid class of insecticide. Toxic effects of cypermethrin were studied by selectingMarcia opimaas an animal model. Cypermethrins effect on the total glycogen content of mantle, gill, foot, hepatopancreas, male gonad and a female gonad of an estuarine clam,Marcia opimawas examined. The clams were exposed to 1.58 ppm cypermethrin for acute and1/th of that concentration for chronic treatment. It was found that there was a decrease in glycogen content in various tissues as compared to control. In LC0and LC50groups, glycogen was decreased in all tissues except in hepatopancreas compared to control. This decrease is greater in mantle, gill, and foot in LC50group than the decrease in those tissues of LC0group. In chronic exposure it was found that glycogen was decreased in mantle, foot, male gonad, and female gonad when compared to the control group except in gill and hepatopancreas. Decrease in glycogen content indicates greater utilization of glycogen for metabolic purposes and too combat with cypermethrin stress. The significant increase in glycogen content in gill and hepatopancreas may be a reaction to the increase in energy demand.