An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst-Reference-Cited by-同舟云学术

An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst

Published:2013-09-02 Issue: Volume:2013 Page:1-5
ISSN:2090-5157
Container-title:ISRN Organic Chemistry
language:en
Short-container-title:ISRN Organic Chemistry

Author:

Banothu Janardhan¹,Gali Rajitha¹,Velpula Ravibabu¹,Bavantula Rajitha¹,Crooks Peter A.²

Affiliation:

1. Department of Chemistry, National Institute of Technology, Warangal, Andhra Pradesh 506 004, India

2. Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA

Abstract

Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of this method.

Funder

University Grants Commission

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/archive/2013/616932.pdf

Reference27 articles.

1. Synthesis, single crystal X-ray studies and antimicrobial activities of novel Indole barbiturates

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