Applications of Dendrimers in Drug Delivery Agents, Diagnosis, Therapy, and Detection

Author:

Noriega-Luna B.1,Godínez Luis A.1,Rodríguez Francisco J.1,Rodríguez A.1,Zaldívar-Lelo de Larrea G.2,Sosa-Ferreyra C. F.2,Mercado-Curiel R. F.2,Manríquez J.1,Bustos E.1

Affiliation:

1. Centro de Investigación y Desarrollo Tecnológico en Electroquímica S.C., Parque Tecnológico Querétaro s/n, Sanfandila, 76703 Pedro Escobedo, QRO, Mexico

2. Medicine Faculty, Universidad Autónoma de Querétaro, Fraccionamiento Prados de la Capilla, 76176 Santiago de Querétaro, QRO, Mexico

Abstract

In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three-dimensional architecture of dendrimers can incorporate a variety of biologically active agents to form biologically active conjugates. This review of dendrimers focuses on their use as protein mimics, drug delivery agents, anticancer and antiviral therapeutics, and in biomedical diagnostic applications such as chemically modified electrodes.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Hindawi Limited

Subject

General Materials Science

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