Magnetic Properties and Biological Activity Evaluation of Iron Oxide Nanoparticles-Reference-Cited by-同舟云学术

Magnetic Properties and Biological Activity Evaluation of Iron Oxide Nanoparticles

Published:2013 Issue: Volume:2013 Page:1-7
ISSN:1687-4110
Container-title:Journal of Nanomaterials
language:en
Short-container-title:Journal of Nanomaterials

Author:

Prodan Alina Mihaela¹²,Iconaru Simona Liliana³⁴⁵,Chifiriuc Carmen Mariana⁶,Bleotu Coralia⁷,Ciobanu Carmen Steluta³,Motelica-Heino Mikael⁵^ORCID,Sizaret Stanislas⁵,Predoi Daniela³

Affiliation:

1. Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari, Sector 5, Bucharest, Romania

2. Emergency Hospital Floreasca, Bucharest 5, Calea Floreasca Nr 8, Sector 1, Bucharest, Romania

3. National Institute of Materials Physics, 105 bis Atomistilor, P.O. Box MG 07, 077125 Bucuresti-Magurele, Romania

4. Faculty of Physics, University of Bucharest, 405 Atomistilor, CP MG-1, 077125 Magurele, Romania

5. ISTO, Université d'Orléans, Orléans Cedex 02, 45067, France

6. Microbiology Department, Faculty of Biology, University of Bucharest, Aleea Portocalelor 1-3, 60101 Bucharest, Romania

7. Institute of Virology, Antiviral Therapy Department “Stefan S. Nicolau”, 285 Mihai Bravu, 030304 Bucharest, Romania

Abstract

The aim of this study was to provide information about the biological properties of iron oxide nanoparticles (IO-NPs) obtained in an aqueous suspension. The IO-NPs were characterized by transmission electron microscopy (TEM). Analysis of hysteresis loops data at room temperature for magnetic IO-NPs sample indicated that the IO-NPs were superparamagnetic at room temperature. The calculated saturation magnetization for magnetic iron oxide wasMs= 18.1 emu/g. The antimicrobial activity of the obtained PMC-NPs was tested against Gram-negative (Pseudomonas aeruginosa1397,Escherichia coliATCC 25922), Gram-positive (Enterococcus faecalisATCC 29212,Bacillus subtilisIC 12488) bacterial as well as fungal (Candida krusei963) strains. The obtained results suggested that the antimicrobial activity of IO-NPs is dependent on the metallic ions concentrations and on the microbial growth state, either planktonic or adherent. The obtained IO-NPs exhibited no cytotoxic effect on HeLa cells at the active antimicrobial concentrations.

Funder

Ministerul Educatiei Nationale

Publisher

Hindawi Limited

Subject

General Materials Science

Link

http://downloads.hindawi.com/journals/jnm/2013/893970.pdf

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