1. Department of Veterans Affairs Iowa City Health Care System, University of Iowa, Iowa City, IA 52246, USA
2. Department of Internal Medicine, University of Iowa, Iowa City, IA 52246, USA
3. Ina Sue Perlmutter Laboratory, Department of Pediatrics and Medicine, Harvard Medical School, Children's Hospital, Boston, MA 02115, USA
4. Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA