A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course

Author:

He Ying1ORCID,White Marvin2,Gang Wu3ORCID,Yan Song4

Affiliation:

1. Institute of Chemical and Pharmaceutical Engineering, Changzhou Vacational Institute of Engineering, Changzhou, Jiangsu 213164, China

2. Department of Information Engineering, Southern University and A&M College, Baton Rouge, LA, USA

3. Langfang Health Vocational College, Langfang, Hebei, China

4. Beijing Sports University, Beijing, China

Abstract

Biological separation and purification technology is the basic technology of modern biotechnology, which is widely used in the pharmaceutical industry, especially the biopharmaceutical industry. In recent years, the biopharmaceutical industry has had a lot of room for development in the development of science and technology in South Korea, and the research on biopharmaceutical equipment and pharmaceutical technology has also achieved good research results. This article proposes a brief discussion on the design of biopharmaceutical separation and purification technology courses. In this study, by analyzing the synthesis potential of the secondary metabolites of the strain, using the α-glucosidase inhibition rate as an inspection indicator, the fermentation medium of the strain was optimized, and batch fermentation was carried out, and then, the metabolites were separated and purified, and the following conclusion was obtained: the α-glucosidase inhibition rate of the crude extract of the strain in the optimized fermentation medium is 35% higher than that of the initial medium.

Publisher

Hindawi Limited

Subject

Health Informatics,Biomedical Engineering,Surgery,Biotechnology

Reference9 articles.

1. Isolation and purification of an antibacterial protein from immune induced haemolymph of American cockroach, Periplaneta americana;H. R. Basseri;Journal of Arthropod-Borne Diseases,2016

2. Isolation and purification treatments change the metal-binding properties of humic acids: effect of HF/HCl treatment;W. G. Botero;Environmental Chemistry,2018

3. Correction to α-glucosidase inhibitors from brickellia cavanillesii;S. Escandón-Rivera;Journal of Natural Products,2016

4. Polyketides from the mangrove-derived endophytic fungus nectria sp. HN001 and their α-glucosidase inhibitory activity;C. Hui;Marine Drugs,2016

5. Isocoumarins and benzofurans from the mangrove endophytic fungus Talaromyces amestolkiae possess α-glucosidase inhibitory and antibacterial activities

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