Author:
Smolanka Ivan Ivanovich, ,Movchan Oleksii Volodimirovich,Bagmut Irina Yuriivna,Sheremet Michael Ivanovich,Kolisnyk Igor Leonidovich,Dosenko Irina Viktorivna,Lyashcnko Andriy Oleksandrovich,Ivankova Oksana Mykolaivna,Loboda Anton Dmitrovich,Shidlovskyi Oleksandr Viktorovich, , , , , , , , , ,
Abstract
We aimed to analyze the frequency of breast cancer relapses and their relationship with molecular and biological tumor characteristics. We studied 6,136 breast cancer patients, including 146 with relapses (Group 1) and 455 without relapses (Group 2). We divided the patients based on age, menstrual function, disease stage, histology form and grade, and molecular-biological subtype. The 5-year relapse-free rate for Group 1 was longer for Lum A and TN subtypes (60% and 40%, respectively) but shorter for Lum B and HER-2/neu-amplified subtypes (38% and 31%, respectively). Disease stage, tumor histology, and grade did not significantly affect relapse frequency in these patients. Relapses were more common in premenopausal patients and the Lum B subtype.
Publisher
S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L
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