The Predictive Value of Systemic Inflammation Markers for the Success of Labor Induction with Foley Catheter

Abstract

Objective: To investigate the predictive value of systemic inflammatory markers for the success of labor induction with foley catheter. Material and Method: Low-risk pregnancies with a single, live, vertex presentation at ≥37 weeks of gestation who underwent labor induction with a foley catheter were included in this retrospective cohort study. Delivery by cesarean section after labor induction was considered as induction failure. The study population was divided into two groups as those who delivered vaginally after labor induction and those who delivered by cesarean section. Demographic and clinical characteristics, prepartum complete blood count values, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio of the two groups were compared. Results: A total of 308 pregnant women were included in the study. Vaginal delivery was performed in 159 (51.6%) of the cases after labor induction, while pregnancy was terminated by cesarean section in 149 (48.4%) cases. The rate of nulliparity was found to be higher in cases who delivered by cesarean section (68.5%) than those who delivered vaginally (54.1%) (p = 0.01). There was no statistically significant difference between leukocyte counts (9804.9 ± 3283.4 h/mm3 vs. 10437.1 ± 4439.8 h/mm3), neutrophil/lymphocyte ratio (4.7 ± 4.1 vs. 4.4 ± 3.9) and platelet/lymphocyte ratio (149.3 ± 67.0 vs. 139.3 ± 50.1) of cases who delivered vaginally and required cesarean delivery (p>0.05). Conclusion: There was no significant relationship between systemic inflammation markers measured before labor induction and labor induction success. However, nulliparity was found to be a risk factor for the failure of labor induction with foley catheter.