Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)
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Published:2020-09-30
Issue:157
Volume:29
Page:200287
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ISSN:0905-9180
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Container-title:European Respiratory Review
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language:en
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Short-container-title:Eur Respir Rev
Author:
Bai ChunxueORCID, Chotirmall Sanjay H.ORCID, Rello JordiORCID, Alba George A.ORCID, Ginns Leo C., Krishnan Jerry A., Rogers Robert, Bendstrup ElisabethORCID, Burgel Pierre-RegisORCID, Chalmers James D., Chua Abigail, Crothers Kristina A., Duggal Abhijit, Kim Yeon WookORCID, Laffey John G.ORCID, Luna Carlos M.ORCID, Niederman Michael S., Raghu Ganesh, Ramirez Julio A., Riera JordiORCID, Roca Oriol, Tamae-Kakazu MaximilianoORCID, Torres AntoniORCID, Watkins Richard R., Barrecheguren Miriam, Belliato Mirko, Chami Hassan A., Chen Rongchang, Cortes-Puentes Gustavo A., Delacruz Charles, Hayes Margaret M., Heunks Leo M.A., Holets Steven R., Hough Catherine L., Jagpal Sugeet, Jeon KyeongmanORCID, Johkoh Takeshi, Lee May M.ORCID, Liebler Janice, McElvaney Gerry N., Moskowitz AriORCID, Oeckler Richard A., Ojanguren Iñigo, O'Regan Anthony, Pletz Mathias W.ORCID, Rhee Chin KookORCID, Schultz Marcus J., Storti Enrico, Strange Charlie, Thomson Carey C., Torriani Francesca J., Wang Xun, Wuyts WimORCID, Xu TaoORCID, Yang Dawei, Zhang Ziqiang, Wilson Kevin C.
Abstract
BackgroundCoronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.MethodsAn International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion.ResultsThe Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder.ConclusionsThe Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities.
Publisher
European Respiratory Society (ERS)
Subject
Pulmonary and Respiratory Medicine
Reference92 articles.
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